Store:Dry and cool place, keep far away from sunlight
Usage: As an intermediate
Payment terms:T/T via bank transfer,Bitcoin,USDT,Western Union
Package:1kg/aluminium foil bag,25kg/box/barrel
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Procaine (Procaine), sold under the name Novocaine (Novocaine), is a local anesthetic. Originally used to relieve pain caused by intramuscular injections of penicillin, it is also used in dental surgery. The main role is sodium channel blockers .
Procaine was first synthesized in 1905 by German chemist Alfred Einhorn , a little later than amilocaine . Alfred Einhorn gave it the Latin name Novacaine (Nova- 'new', -caine a common suffix for an alkaloid with narcotic effects). It was introduced to clinical use by surgeon Heinrich Braun, and cocaine was the most commonly used local anaesthetic before the advent of stovaline (also known as Amylocaine) and procaine.
Local anesthetic is the main use of procaine. Procaine has been withdrawn from the US market due to the advent of the more effective local anesthetic lidocaine, which is no longer commonly used . Like other local anesthetics such as Mepivacaine and Prilocaine, procaine is a vasodilator, often used with epinephrine to narrow blood vessels.
Side effects and adverse reactions
Chemical synthesis method
Procaine can be synthesized in two ways. The first is the transesterification reaction between ethyl p-aminobenzoate and N,N' -dimethyl-2-aminoethanol under the catalysis of sodium glycolate. The second method is to first convert p-nitrobenzoic acid into a pair of nitrobenzoyl chloride with sulfoxide chloride, then the acid chloride with N,N' -dimethyl-2-amino-ethanol to get p-nitrobenzoic acid ester, and finally with Raney nickel to reduce the nitro group to the amino group to get the product
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